Mini-Symposia Session III - Friday, October 9

  • 13. Cell Interactions
    Chaired by Ken Yamada, NIDR, and Stephen Shaw, NCI
    Friday, October 9
    10:30 a.m.-12:30 p.m.
    Natcher Conference Center
    Conference Room F1/F2
    Martin Brown, NCI
    Coordinated Assembly of Cytoskeletal and Signaling Molecules during T-Cell Receptor Stimulation

    Ben-Zion Katz, NIDR
    Adhesion-Mediated Regulation of Cytoskeletal Assembly

    Matthew Hoffman, NIDR
    Growth Factor-Matrix Synergy in Cell Differentiation

    Mark Udey, NCI
    E-Cadherin and Leukocyte-Epithelial Interactions

    Kim Yancey, NCI
    What an Inherited Blistering Disease Has Taught Us about Epidermal Adhesion

  • 14. Characterization of Biologic Mediators by Spectroscopic Methods
    Chaired by Sandy Markey, NIMH, and H-Y Kim, NIAAA
    Friday, October 9
    10:30 a.m.-12:30 p.m.
    Natcher Conference Center
    Balcony A
    James Kelley, NCI
    Mass Spectrometric Studies of Nucleoside Metabolism in the Development of New Drugs for AIDS

    K. Gustafson, NCI and L. Pannell, NIDDK
    Structural Elucidation of Anti-HIV Proteins and Peptides

    Martin Garraffo and Tom Spande, NIDDK
    Application of CI-MS/MS to the Structure Elucidation of Alkaloids

    Robert Crouch, Jeffrey Kowalak, and Alfred Yergey, NICHD
    Mass Spectrometric Analysis of Proteins Captured by Biosensors

    Ettore Appella, NCI
    Isolation and Characterization of Bioactive MHC Peptides

  • 15. DNA Repair and Mutagenesis
    Chaired by Vilhelm Bohr (NIA) and Tom Kunkel (NIEHS)
    Friday, October 9
    10:30 a.m.-12:30 p.m.
    Natcher Conference Center
    Balcony B
    Vilhelm Bohr, NIA
    DNA Repair and Transcription in Human Premature Aging Syndromes

    Samuel Wilson, NIEHS
    DNA Transactions During Repair of Endogenous DNA Lesions

    Martin Gellert, NIDDK
    Linkage of V(D)J Recombination to Double Strand Break Repair and Transposition

    Peggy Hsieh, NIDDK
    Heteroduplex DNA Recognition by the Mut S Mismatch Repair Protein

    Al Fornace, NCI
    cDNA Microarray Hybridization Reveals Complexity and Heterogeneity of Cellular Genotoxic Stress Responses

  • 16. Gene Regulatory Proteins
    Chaired by Roland Owens, NIDDK, and Ana B. Chepelinsky, NEI
    Friday, October 9
    10:30 a.m.-12:30 p.m.
    Natcher Conference Center
    Conference Room E1/E2
    Ana B. Chepelinsky, NEI
    AP2" Isoforms and Sp Family of Transcription Factors Expression in the Ocular Lens

    Alfred C. Johnson, NCI
    GCF2: A Negative Regulator of Epidermal Growth Factor Receptor Gene Expression

    S. Stoney Simons, Jr., NIDDK
    Role of the Novel Proteins GMEB-1 and -2 in the Modulation of Glucocorticoid Regulated Gene Transcription

    Kevin L. Gardner, NCI
    CREB/REL Crosstalk Couples p300/CBP Recruitment to Oncogenic Molecular Signaling in T Lymphocytes

    Roland A. Owens, NIDDK
    Protein-DNA Complexes at the Proximal YY1 Site of the Adeno-Associated Virus p5 Promoter in the Presence or Absence of Adenovirus

    Alison McBride, NIAID
    The Papillomavirus E2 Transcriptional Transactivator is also Important for Initiation of Viral DNA Replication and Segregation of Episomal Viral Genomes
    Charles E. Egwuagu, NEI
    Members of the IRF Family of Transcription Factors are Constitutively Expressed and Differentially Regulated in the Mouse Lens

  • 17. Modulation of Receptor, Ion Channel, and Transporter Function
    Chaired by Forrest Weight, NIAAA, and Michael Rogawski, NINDS
    Friday, October 9
    10:30 a.m.-12:30 p.m.
    Natcher Conference Center
    Main Auditorium
    Chaoying Li, NIAAA
    Modulation of ATP-Gated Membrane Ion Channels (P2X Receptors) by Endogenous Agents

    Mark L. Mayer, NICHD
    Polyamine Block of Glutamate Receptor-Channels

    Michael A. Rogawski, NINDS
    Modulation of Excitatory Amino Acid Receptors for Treatment of Neurological Disorders

    George R. Uhl, NIDA
    Rapid Temporal Regulation of Opiate and Psychostimulant Recognition Sites: Phosphorylation, Desensitization and Down-Regulation of Mu-Opiate Receptor and Dopamine Transporter

    Jerrel L. Yakel, NIEHS
    Modulation of Calcium Channel Function by G-Protein Coupled Receptors

  • 18. Post-Transcriptional Control of Gene Expression
    Chaired by Alan Hinnebusch, NICHD, and Ellie Ehrenfeld, NIAID
    Friday, October 9
    10:30 a.m.-12:30 p.m.
    Natcher Conference Center
    Balcony C
    Harris Bernstein, NIDDK
    The Function of the Signal Recognition Particle in E. coli

    Susan Gottesman, NCI
    Title TBA

    Tom Dever, NICHD
    A Bacterial IF2 Homolog in Eukaryotic Cells Facilitates Met-tRNA Binding to Ribosomes

    Tracey Rouault, NICHD
    Title TBA

    Carl Baker, NCI
    Title TBA

    Hui Ge, NHGRI
    A Novel Transcriptional Coactivator, p52, Functionally Interacts with the Essential Splicing Factor ASF/SF2


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